Joel Moss

Title: 
Professor, M.D.,Ph.D.
Profile: 

 

Education:

1963-1966 B.A. with Honors in Chemistry, summa cum laude, Brandeis University, Waltham, Mass.; studies completed in three years, degree conferred in June, 1967

1966-1972 M.D.-Ph.D., New York University School of Medicine; dissertation in the Department of Biochemistry

 

Employment:

1972-1974 Medical intern and resident, Johns Hopkins Hospital, Baltimore, MD 21205

1974-1977 Research Associate and Pulmonary Fellow, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892

1977-1979 Staff Investigator, Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892

1979-1994 Head, Section on Molecular Mechanisms, Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892

1979-1994 Physician, Medical Intensive Care Unit, Clinical Center, National Institutes of Health, Bethesda, MD 20892

1986-1994 Deputy Chief, Laboratory of Cellular Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892

1993-1994 Acting Chief, Pulmonary Branch, National Heart, Lung, and

Blood Institute, National Institutes of Health, Bethesda, MD

1994-2007 Chief, Pulmonary-Critical Care Medicine Branch, National Heart,

Lung, and Blood Institute, National Institutes of Health,

Bethesda, MD

2007-2010 Deputy Chief, Translational Medicine Branch, National Heart,

Lung, and Blood Institute, National Institutes of Health,

Bethesda, MD

2007- Head, Translational Research Section, National Heart,

Lung, and Blood Institute, National Institutes of Health,

Bethesda, MD

2007- Head, LAM Research Program, National Heart,

Lung, and Blood Institute, National Institutes of Health,

Bethesda, MD

2010- Deputy Chief, Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

2014(Dec) – Interim Deputy Clinical Director, Cardiovascular and

2015(Feb) PulmonaryBranch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

 

Professional Certification:

1975 Diplomate in Internal Medicine

1978 Diplomate in Pulmonary Disease

1987-1997 Diplomate in Critical Care Medicine

 

Honors and Awards:

1963 New York State Regents Scholarship

1964-1965 Louis D. Brandeis Honorary Scholar

1966 Phi Beta Kappa

1966 New York State Regents Scholarship for Professional Study

1966 New York University School of Medicine Admission Scholarship Award

1967 Melvin M. Snider Graduation Chemistry Award

1970 American Oil Chemists' Society Honored Student Award

1973 Founder's Day Award, New York University

1981 Passano Foundation Young Scientist Award for 1981

1982 Public Health Service Commendation Medal

1985 Cancer Research Campaign Lecture, Third Annual Workshop on ADP-ribosylation of Protein, Reading, U.K.

1987 American Federation for Clinical Research Young Investigator Award for Clinical Research

1989 Public Health Service Meritorious Service Medal

1996 Introductory Speaker, "Biological Significance of Mono-ADP-ribosylation in Animal Tissues" Hamburg, Germany; May 19-23, 1996.

1996 Visiting Lecturer, Alberta Heritage Foundation for Medical Research, University of Calgary, Alberta, Canada

1998 National Institutes of Health Director’s Award

1999 LAM Foundation Award

2000 Honorary Member, Peruvian Thoracic Society

2003 EEO Special Achievement Award

2004 Chiba University School of Medicine/Chiba Medical Society Silver Medal

2007 New York University School of Medicine: Alumnus Inductee of the Alpha Omega Alpha (AOA) Honor Society Delta Chapter of New York

2009 New York University School of Medicine: The Solomon A. Berson Medical Alumni Achievement Award in Basic Science

2009 Elected to John Hopkins University Society of Scholars

2010 LAM Foundation Scientific Achievement Award

2010 Fellow, American College of Chest Physicans

2012 Orloff Science Award, NHLBI Division of Intramural Research, Team Lead: For molecular insights that led to target therapies for lymphangioleiomyomatosis (LAM)

2012 Chiba Medical Society Award, Chiba, Japan

2013 Learning Environment Award, NHLBI Director’s Award, Bethesda, MD.

 

Professional Affiliations:

Member, American Society of Biological Chemists (1977)

Member, American Society for Clinical Investigation (1979)

Member, Association of American Physicians (1991)

Member, American Thoracic Society (1993)

Member, American College of Chest Physicians (2010)

 

Elected Advisory Positions:

1987-1990 Councillor, American Society for Clinical Investigation

1990-1991 Vice-President, American Society for Clinical Investigation

 

NIH Intramural Advisory Committees:

1980-1981 Secretary, Assembly of Scientists, NHLBI

1988-2006 Institutional Review Board, NHLBI

1988-2004 Promotion Tenure Review Board, NHLBI

1988 Organizing Committee, NIH Research Day

1989-1994 Pharmacology Research Associate (PRAT) Program Advisory Committee

1991-present Advisor, NRC Research Associateship Program

1994-present Subcommittee on Cooperative Research and Development Agreements, NIH Patent Policy Board

1994-present Technology Evaluation Advisory Committee

1994-1995 Chair, Pharmacology Research Associate Program Advisory

Committee

1995 NHLBI Transgenic Support Service Committee

1995 NIDR Tenure Track Advisory Committee

1995-1998 Howard Hughes Medical Institute-NIH Research Scholars Program Advisory Committee

1995-2006 Chair, NHLBI Institutional Review Board (IRB)

1996 Member, Committee on Recruitment of Clinical Researchers, NIH

1996-2002 Member, General Loan Repayment Committee, NIH

1997 Member, Committee on Extramural/Intramural Investigations in the Clinical Center, NIH

1997 Search Committee: NHLBI, Veterinarian

1997-present Member, Advisory Committee for Clinical Researchers for the Central Tenure Committee, NIH, IR

1997 Member, Senior Executive Search Committee, Deputy Director, NHLBI

2002 Member, Tenure Track Search Committee, Cardiovascular Branch,

NHLBI

2002 Chair, Clinical Director Search Committee, NHLBI

2002 Member, Panel, Biomedical Research Training Program for

Underrepresented Minorities (BRTPUM), NHLBI

2002-present Proteomic Core Committee

2002-present Pathology Core Committee

2003-2005 Chair: Title 42 Standing Committee

2005-present Clinical Research Training Program Admission Committee

2006 Member, Panel 3, NIH IC Symposium on Population Genomics

2006 Member, NHLBI Strategic Planning Process – Lung Program

Theme #4 Working Group: Personalized Medicine

2006- Member, Trans-NIH Coordinating Committee for Lymphatic Research

2006-2007 Clinical Imaging Sciences Department Search Committee

2007- GAIN Data Access Committee

2007-2008 Member, NHLBI Tenure Track Search Committee for Clinical Research

2008- Chair, Pathology Core Steering Committee

2008-2009 Member, Pulmonary Medicine Branch Chief Search Committee

2008-2009 Member, DIR Data Management Advisory Group

2009 Member, Earl Stadtman Tenure Track Investigator Search Committee:

Clinical Research

2009-2010 Member of PHEMCE Chemical Requirements WG, Biomedical

Advanced Research & Development Authority (BARDA)

2010 Member, Earl Stadtman Tenure Track Investigator Search Committee:

MolecularBiology/Biochemistry Committee

2011- Member, FACS Core Steering Committee

2011 Member, Stadtman Tenure-track Search Committee for Molecular Biology and Biochemistry

2011-2012 Member, Working Group for NIH Performance Management Appraisal Program (PMAP)

2012 Member, Earl Stadtman Search Committee – Molecular Biology/Biochemistry

2012-2013 Member, NHLBI Clinical Director Search Committee

2012- Member, Technology Transfer Policy Board (alternate for Dr. Gerfen Chair, CRADA subcommittee)

2012- Member, NHLBI Search Committee for Staff Clinican

2013 Member, Earl Stadtman Search Committee – Molecular Biology/Biochemistry

2014 Member, Earl Stadtman Search Committee – Molecular Biology/Biochemistry

 

Editorial Positions:

1982-1987 Editorial Board, Journal of Biological Chemistry

1985 Co-editor, "Pertussis Toxin", Academic Press, Inc., New York, NY

1990 Co-editor of "ADP-ribosylating Toxins and G Proteins", (American

Society for Microbiology, Washington, D.C., publishers)

1991-1996 Editorial Committee, The Journal of Clinical Investigation

1992-1997 Editorial Board, Journal of Biological Chemistry

1994 Co-Editor, "ADP-Ribosylation: Metabolic Effects and Regulatory Functions", focused issue of Molecular and Cellular Biochemistry, Kluwer Academic Publishers, Dordrecht, The Netherlands

1995 Co-editor of "Handbook of Bacterial Toxins", Volume 8 (Marcel Dekker, Inc., New York, New York, Publishers)

1998- Editorial Board, American Journal of Respiratory Cell & Molecular Biology

1998-2003 Editorial Board, Journal of Biological Chemistry

1998-Present Editorial Board, The American Journal of the Medical Sciences

1999 Editor, "LAM and Other Diseases Characterized by Smooth Muscle Proliferation" for the series "Lung Biology in Health and Disease", executive editor, Claude Lenfant, Marcel Dekker, New York, New York

2000 Co-editor, "Paroxysmal Nocturnal Hemoglobinuria", Academic Press, San Diego, California

2001 Editor, "Clinical Insights from Uncommon Lung Diseases", focused issue of The American Journal of The Medical Sciences. Decatur, Georgia, 2002

2002 Co-author with Jordan Prutkin of text “Genetics for Pulmonologists.”

Remedica, London, United Kingdom.

2003- Associate Editor, Encyclopaedia of Respiratory Medicine, Elsevier, Oxford, UK.

2005- Faculty Member, Faculty of 1000 Medicine, United Kingdom, 2005.

2005 Editor, Encyclopedia of Dietary Supplements (1st edition), Marcel Dekker, New York.

2006 Co-author with Dr. Evan DeRenzo of “Writing Clinical Research

Protocols: Ethical Considerations.” Elsevier, Academic Press, San Diego, CA, 2006.

2007-2012 Editorial Board, CHEST

2007 - External Reviewer, Canadian Cystic Fibrosis Foundation, Toronto, Ontario, Canada.

2009- Section Editor in Signalling for the Encyclopaedia of Biological Chemistry, Elsevier, Burlington, MA.

2010- Foreign Editor, Tohoku Journal of Experimental Medicine

2010 Guest Editor, Lymphatic Research and Biology, focused issue on LAM

2010-2015 Associate Editor, CHEST

2010 Editor, Encyclopedia of Dietary Supplements (2nd edition),Informa Healthcare, New York, London.

2014- Member, International Advisory Board, Juntendo Medical Journal, Tokyo, Japan.

 

Direction of Research:

1) Reconstitution of protein trafficking systems with 20-kDa guanine nucleotide-binding ADP-ribosylation factors and associated regulatory proteins.

2) Role of bacterial virulence factors in lung disease.

3) Genetic factors in lung disease.

4) Pathogenesis of lymphangioleiomyomatosis (LAM).

5) Regulation of ADP-ribosylation cycles in animal cells; characterization and cloning of ADP-ribosyltransferases, ADP-ribosylarginine hydrolases and their substrates.

Institution(s)/organization(s): 

Cardiovascular and Pulmonary Branch
National Heart, Lung, and Blood Institute
National Institutes of Health

Editorial Role: 
Country/Area: