Sibel Köktürk

Title: 
M.D.,PhD.
Profile: 

Dr. Sibel Köktürk received the M.D and Ph.D degree in Histology and Embriyology from the Kocaeli University, Faculty of  Medicine and Istanbul University, Cerrahpaşa Faculty of  Medicine in Turkey, in 1998 and 2004, respectively. She currently serves as an Associate Professor in the Ordu University, Faculty of Medicine in Turkey. Her research interests include neuroscience, epilepsy, cell biology, pathology, experimental medicine, immunology, toxicology, stem cell, imaging analyses, immunohistochemistry.
    

Work experience
2011 − present
Research assistant    Kocaeli University, Faculty of Medicine,
Department of Histology and Embriyology
    1995-1998
Research assistant    Istanbul University, Cerrahpaşa Faculty of Medicine,
Department of Histology and Embriyology
    1999-2004
Research assistant    Kocaeli University
    2005-2006
Assistant Professor    Kocaeli University
    2007-2010
Assistant Professor    Ordu University, Faculty of Medicine,
Department of Histology and Embriyology
    2011-2014
Associate Professor     Ordu University, Faculty of Medicine,
Department of Histology and Embriyology    2014- present

Memberships
The member of the Turkish Society for electron microscopy
The member of the Turkish Society for Histology and Embriyology

Awards, Distinctions and Fellowships

1-    The Continental European Division (CED) Travel Stipend Award. 4th meeting of Continental European Division of the the International Association for Dental Research, 2008.

2-    The 1st award for best research of Turkish Ophthalmology Society. 43th national Ophthalmology Congress, 2009.

3-    Prof.Dr. Afet Solmaz Özoran Poster award. Turkish Society for electron microscopy, 2009.

 

Research Interests
Neuroscience, Epilepsy, Cell Biology, Pathology, Experimental Medicine, Immunology, Toxicology, Stem cell, Imaging Analyses, Immunohistochemistry.  

Publications
1.    S. Gonca, S. Ceylan, M. Yardımoğlu, H. Dalçık, Z. Yumbul, S. Köktürk, S. Filiz. Protective effects of vitamin E and selenium on the renal morphology in rats fed high cholesterol diets. Pathobiology, 2000; 68(6): 258-63. Doi numarası: 10.1159/000055935.

2.    S. Gonca, S. Ceylan, M. Yardımoğlu, H. Dalçık, Z. Yumbul, S. Köktürk, S. Fılız. Histopathological Effects Of Cholesterol And Protective Effects Of Vitamin E And Selenium On The Morphology Of Rat Liver. Turkish Jornal Of Medical Science, 30: 551-555, 2000.
3.    H. Dalçık, M. Yardımoğlu, B. Vural, C. Dalçık, S. Köktürk, S. Gonca, S. Filiz. Expression of insulin-like growth factor in the placentae of intrauterine growth retarded human fetuses. Acta Histochemica. 2001 Apr; 103(2): 195-207. Doi numarası: 10.1078/0065-1281-00580.
4.    A. Çolak, A. Karaoğlan, Ş. Barut, S. Köktürk, A. İ. Akyıldız, M. Taşyürekli. Neuroprotection and functional recovery after application of the caspase-9 inhibitor z-LEHD-fmk in a rat model of traumatic spinal cord injury. Journal of Neurosurgery Spine, 2005 Mar; 2(3): 327-334.
5.    M. Yardimoglu, G. Ilbay, S. Kokturk, F. D. Onar, D. Sahin, F. Alkan, H. Dalcik. Light and Electron Microscopic Examinations In The Hippocampus Of The Rat Brain Following Ptz-Induced Epileptic Seizures. Journal of Applied Biological Sciences, 1(3): 97-106, 2007.

6.    A. Karaoglan, O. Akdemir, S. Barut, S. Kokturk, H. Uzun, M. Tasyurekli, A Colak. The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats. Surgical Neurology. 2008 Oct; 70(4): 337-43. doi: 10.1016/j.surneu.2007.07.031.

7.    A. Colak, O. Soy, A. Karaoglan, O. Akdemir, S. Kokturk, A. Sagmanligil, M. Tasyurekli. Effects of GYKI 52466 on early vasospasm in rats. Central European Neurosurgery. 2009 Nov; 70(4): 187-94. doi: 10.1055/s-0029-1202357.

8.    C. Ozkurkcugil, M. Y. Yılmaz, L. Ozkan, S. Kokturk, T. Isken. Protective effects of pentoxifylline on cigarette smoking-induced renal tissue damage in rats. Toxicology and Industrial Health. 2011 May; 27(4):335-40. doi: 10.1177/0748233710387006.

9.    P. K. Iseri, A. Karson, K. M. Gullu, O. Akman, S. Kokturk, M. Yardimoglu, S. Erturk, N. Ates. The effect of memantine in harmaline-induced tremor and neurodegeneration. Neuropharmacology. 2011 Sep; 61(4): 715-23. doi: 10.1016/j.neuropharm.

10.    I. Anik, S. Kokturk, H. Genc, B. Cabuk, K. Koc, S. Yavuz, S. Ceylan, S. Ceylan, L. Kamacı, Y. Anik. Immunohistochemical analysis of TIMP-2 and collagen types I and IV in experimental spinal cord ischemia–reperfusion injury in rats. The Journal of Spinal Cord Medicine. 2011; 34(3):257-264. doi: 10.1179/107902611X12972448729648.

11.    S. Ceylan, I. Anik, K. Koc, S. Kokturk, S. Ceylan, N. Cine, H. Savli, G. Sirin, B. Sam, N. Gazioglu. Microsurgical anatomy of membranous layers of the pituitary gland and the expression of extracellular matrix collagenous proteins. Acta Neurochirurgica. 2011 Dec;153(12):2435-2443. doi: 10.1007/s00701-011-1182-3.
12.    O. Mutlu, E. Gumuslu, G. Ulak, I. Komsuoglu Celikyurt, S.Kokturk, H. Maral Kır, F. Akar, F. Erden. Effects of fluoxetine, tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice. Life Sciences, 2012 Dec 17;91(25-26):1252-1262. doi: 10.1016/j.lfs.2012.09.023.

13.    I. Seckin, M. Uzunalan, M. Pekpak, S. Kokturk, H. Sonmez, Z. Ozturk, S. Demirci, E. Yaprak. Experimentally induced puromycine aminonucleoside nephrosis (PAN) in rats: evaluation of angiogenic protein platelet-derived endothelial cell growth factor (PD-ECGF) expression in glomeruli. Journal of Biomedical Science. 2012 Feb 16;19-24. doi: 10.1186/1423-0127-19-24.

14.    S. Köktürk, S. Ceylan , V. Etus, N. Yasa, S. Ceylan. Morinda citrifolia L. (noni) and memantine attenuate periventricular tissue injury of the fourth ventricle in hydrocephalic rabbits. Neural Regeneration Research. 2013; 8(9):773-782. doi:10.3969/j.issn.1673-5374.2013.09.001.

15.    S. Köktürk, M. Yardımoglu, S. D. Celıkozlu, E. Dolanbay, A. Cımbız. Effect of Lycopersicon esculentum extract on apoptosis in the rat cerebellum, following prenatal and postnatal exposure to an electromagnetic field. Experimental and Therapeutic Medicine. 2013; 6: 52-56, DOI: 10.3892/etm.2013.1123.

16.    Oguz Mutlu, Guner Ulak, Sibel Kokturk, Ipek Komsuoglu Celikyurt, Furuzan Akar, Faruk Erden. Effects of homeopathic Anax imperator on behavioural and pain models in mice. Homeopathy, 01/2014.

17.    Topdag M, Iseri M, Topdag DO, Kokturk S, Ozturk M, Iseri P. The Effect of Etanercept and Methylprednisolone on Functional Recovery of the Facial Nerve After Crush Injury. Otol Neurotol. 2014 Apr 24.

18.    Oguz Mutlu, Guner Ulak, Sibel Kokturk, Ipek Komsuoglu Celikyurt, Pelin Tanyer, Furuzan Akar, Faruk Erden. Effects of a dragonfly (Anax i.) homeopathic remedy on learning, memory and cell morphology in mice . Homeopathy.  August 23, 2015. DOI: http://dx.doi.org/10.1016/j.homp.2015.07.004.

19.    Oguz Mutlu, Esen Gumuslu, Sibel Kokturk, Guner Ulak, Furuzan Akar, Faruk Erden, Havva Kaya and Pelin Tanyeri. Effects of chronic administration of adipokinetic and hypertrehalosemic hormone on animal behavior, BDNF and CREB expression in the hippocampus and neurogenesis in mice. Fundamental & Clinical Pharmacology. 23 NOV 2015. DOI: 10.1111/fcp.12165.

20.    Benli E, Ayyildiz SN, Cirrik S, Koktürk S, Cirakoglu A, Noyan T, Ayyildiz A, Germiyanoglu C.  The effect of tadalafil therapy on kidney damage caused by sepsis in a polymicrobial septic model induced in rats: a biochemical and histopathological study. Int Braz J Urol. 2016 Sep 1. doi: 10.1590/S1677-5538.IBJU.2016.0075.

21.    Fatma Ceyla Eraldemir, Aysun Şengül, Meyrem Özkan, Sibel Köktürk, Doğa Özsoy, Firuzan Akar Yıldız. The anti-inflammatory and anti-remodeling effect of tiotropium bromide in the subacute cigarette exposure mouse model.  Int J Clin Exp Med 2016;9(11):22824-22834.

Conference Papers
1.    H. Dalçık, M. Yardımoğlu, S. Ceylan, B. Vural, C. Dalçık, S. Köktürk, S. Gonca, S. Filiz. Immunocytochemical localization of insulin like growth factor-1 (IGF-1) in human umblical cord. The Eleventh European Anatomical Congress. Sayfa 74, 10-13 September 1998, Timisoara, Romania.

2.    H. Dalçık, M. Yardımoğlu, B. Vural, C. Dalçık, S. Filiz, S. Gonca, S. Köktürk, S. Ceylan. An immunocytochemical study of insulin like growth factor-1 (IGF-1) in the placentae of intrauterine growth retarded human fetuses. XI International Congress of Histochemistry & Cytochemistry, Page 74, 3-8 September 2000, University of York, UK.

3.    İ. Seçkin, M. Uzunalan, M. Pekpak, S. Köktürk, B. Uruluer, S. Sönmez, Z. Öztürk, G. Şatıroğlu. Apoptotic podocytes, mesangial cells and endothelial cells, platelet derived growth factor (PDGF) and transforming growth factor-b (TGF-b) in puromycine aminonucleoside nephrosis wistar rats. Eoropean Renal Association XLI Congress, 238, May 15-18, 2004, Lisbon, Portugal.

4.    İ. Seçkin, M. Uzunalan, M. Pekpak, S. Köktürk, H. Sönmez, Z. Öztürk, G. Şatıroğlu. Platelet derived endothelial cell growth factor expression in puromycine aminonucleoside nephrosis. Nephrology Dialysis Transplantation. 22 (suppl 6): vi103-vi110, Page 108. XLIV Congress of the European Renal Association European Dialysis and Transplant Association (ERA-EDTA), 21-24 June 2007, Barcelona, Spain.
5.    F. Alkan, S. Köktürk, F. Kaya Dağıstanlı, M. Öztürk, M. Uzunalan, B. Uruluer. Mitogenic activity in the ventricular and the subventricular zone of rat brain. Imaging of nerve cell structure and function. XIII. International Congress of Histochemitry and Cytochemistry. P4.14, 841, 27 August, 2008, Gdansk, Poland.

6.    E. Karaöz, A. Patır, A. Eker Sarıboyacı, A. Okcu, S. Köktürk, G. Gacar, P. Cetınalp Demırcan, M. Kasap,  F. Seymen. Characterization and Differentiation of Dental Pulp and PDL Stem Cells. Pan European  Festival of the International  Research Meeting, abstract number 0915(111018), page 228, 10-12 September 2008, London, UK.

7.    A. Eker Sarıboyacı, A. Okcu, S. Köktürk, G. Gacar, M. Kasap, P. Ç. Demırcan, E. Çalışkan, C. Özoğul, E. Karaöz. Isolation, Characterization And Differentation Potential Of Human Amniotic Fluid Derived Multipotent Mesenchymal Stem Cells. 14th Annual Meeting of the European-Hematology-Association. Haematologica-The Hematology Journal,  Volume: 94, Pages 458-459. Supplement: Suppl. 2 Meeting Abstract: 1130, Published: June 2009, June 04-07, 2009, Berlin, Germany.

8.    E. Karaoz, S. Köktürk, A. Sariboyaci , M. Kasap, G. Gacar, P. Ç. Demırcan, A. Okcu, Y. Yazır, C. Ozogul. Comparative Analysis Of Rat Bone Marrow-Derived Mesenchymal Stem Cells Cultured Under Different Conditions. 14th Annual Meeting of the European-Hematology-Association. Haematologica-The Hematology Journal, Volume: 94, Page 460. Supplement: Suppl. 2, Meeting Abstract: 1135, Published: June 2009. June 04-07, 2009, Berlin, Germany.

9.    İ. Seçkin, M. Uzunalan, M. Pekpak, S. Köktürk, B. Uruluer, H. Sönmez, Z. Öztürk. Angiogenesis In Puromycine Aminonucleoside Nephrosis. XLVII ERA-EDTA Congress - II DGfN Congress, 305, June 25-28, 2010, Munich, Germany.

10.    S.Köktürk, M. Y. Yardimoglu, S. D. Celikozlu, E. Gelenli, A. Cimbiz. Effect of Lycopersicon Esculentum Extract on Apoptosis in The Rat Cerebellum Following Prenatal and Postnatal Exposure to Electromagnetic Field. 23. Meeting of the European Neurological Society, P 527, Syf 120, 8-11 June 2013, Barselona, Spain.

11.    E. Benli, S.N. Ayyildiz, S. Cırrık, S. Kokturk, A. Cirakoglu, T. Noyan, A. Ayyildiz, C. Germiyanoglu. In sepsis model formed on rats, does tadalafil protect from renal injury? Europian Association of Urology (EAU) 11th South Eastern European Meeting. 171, Eur Urol Suppl 2015; 14(8): e1445, 6-8 November 2015, Antalya, Turkey.

12.    Köktürk Sibel,  Mutlu Oguz, Ulak Guner, Akar Furuzan,  Erden Faruk,  Celikyurt Ipek,  Bektas Emine, Tanyeri  Pelin. Effects Of Second-Generation Antipsychotics On Neurogenesis and Neurodegeneration in Dentate Gyrus Of The Hippocampus. EBBS (European Brain Behaviour Society) & EBPS (European Behavioural Pharmacology Society) Joint Meeting. Verona, Gran Guardia Palace, Italy. September, 12-15 2015.

13.    Köktürk Sibel, Mutlu Oguz, Akar Furuzan, Ulak Guner,  Erden Faruk, Celikyurt Ipek K. Effects Of Adipokinetic Hormones On Neurogenesis and Neurodegeneration. EBBS (European Brain Behaviour Society) & EBPS (European Behavioural Pharmacology Society) Joint Meeting. Verona, Gran Guardia Palace, Italy. September, 12-15 2015.

14.    Köktürk Sibel, Akar Furuzan, Mutlu Oguz, Ulak Guner, Erden Faruk, Celikyurt Ipek K. Effect Of Odq On Bdnf Immunohistochemistry Staining In Mice. EBBS (European Brain Behaviour Society) & EBPS (European Behavioural Pharmacology Society) Joint Meeting. Verona, Gran Guardia Palace, Italy. September, 12-15 2015.

15.    Cirrik, Selma; Benli, Erdal; Ayyildiz, Sema Nur; Karagüzel Ersagun,Kaçar Ayper,Noyan Tevfık,Ayyıldız Alı, Köktürk Sıbel. The Effect of Tadalafil on Renal Fibrosis Induced by Ureteral Obstruction,  ACTA PHYSIOLOGICA , Volume: 218. Special Issue: SI  Supplement: 709 Pages: 11-11. Published: SEP 2016.

16.    Ece, E; Celikozlu, S; Dayioglu, H; Cayci, M; Kokturk, S; Celikozlu, H; Darcan, S; Ozzaim, C. Does causes 1800 MHz magnetic field application KRAS and P53 mutations in colon?: occurences histopatologically and microbiologically changes in colon. Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEY Date: SEP 03-08, 2016. Sponsor(s): FEBS. FEBS JOURNAL, Volume: 283, Special Issue: SI Supplement: 1,  Pages: 156-157. Meeting Abstract: P05011-015.  Published: SEP 2016. FEBS JOURNAL Volume: 283, Pages: 156-157, Supplement: 1, Special Issue: SI Meeting Abstract: P05011-015. Published: SEP 2016.

Book Chapters
M. Yardimoglu, G. Ilbay, C. Dalcik, H. Dalcik, S. Kokturk. Cellular and Molecular Mechanisms Underlying Epilepsy: An Overview with Our Findings. Epilepsy Histological, Electroencephalographic and Psychological Aspects. Edited by Dr. Dejan Stevanovic, publisher InTech Published. Syf 3-30, INTECHWEB. ORG, ISBN No: 978-953-51-0082-9, Rijeka, Croatia, February, 2012.

Institution(s)/organization(s): 

Ordu University, Faculty of Medicine

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